transformation of: pergolide to pergolide sulfoxide
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
freeze-dried
Type Strain
no
Preceptrol®
no
Comments
11-alpha-Hydroxylation of steroids
Medium
ATCC® Medium 336: Potato dextrose agar (PDA)
Growth Conditions
Temperature: 24.0°C
Sequenced Data
No DNA sequencing was performed in house on this product.
Name of Depositor
Schering Corp.
References
Ilavask J, Herzog HL. 11alpha-hydroxylation of steroids by Beauveria. US Patent 3,013,945 dated Dec 19 1961
Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979.
Hufford CD, et al. Metabolism of imipramine by microorganisms. J. Pharm. Sci. 70: 151-155, 1981. PubMed: 7205217
Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155